Veteran Leander Paes and his partner Samantha Stosur suffered a second round defeat in the mixed doubles event, ending India's campaign at the season's first Grand Slam on Tuesday.
The unseeded pair of Paes and Stosur won the first set 6-4 against Anna-Lena Groenefeld and Robert Farah but conceded the second set with the same scoreline.
The third set went into tiebreak with the fifth seed German-Colombian duo emerging victorious 10-8.
Paes and Stosur had beaten the pair Dutch-Czech pairing of Wesley Koolhof Kveta Peschke in the round of 32.
The 45-year-old Paes had made a first round exit in the men's doubles event with partner Mexican Miguel Angel Reyes-Varela.
Jeevan Nedunchezhiyan and his partner Nicholas Monroe were also knocked out in the opening round of the event.
