Powerful explosions rattled the southern Ukrainian city of Mykolaiv on Thursday and a city close to the country's biggest nuclear power plant sustained a barrage of shelling amid Russian attacks in several regions, Ukraine's presidential office said. At least four civilians were killed and 10 more wounded over the past 24 hours, with nine Ukrainian regions coming under fire, the office said in its daily update.

Two districts of Mykolaiv, which has been targeted frequently in recent weeks, were shelled. Russian forces reportedly fired 60 rockets at Nikopol, in the central Dnipropetrovsk region. Some 50 residential buildings were damaged in the city of 107,000 and some projectiles hit power lines, leaving city residents without electricity, according to Ukrainian authorities.

Nikopol is located across the Dnieper river from the Zaporizhzhia nuclear power plant, which was taken over by Russian troops early in the war.

Experts at the U.S.-based Institute for the Study of War believe that Russia is shelling the area intentionally, “putting Ukraine in a difficult position."

“Either Ukraine returns fire, risking international condemnation and a nuclear incident (which Ukrainian forces are unlikely to do), or Ukrainian forces allow Russian forces to continue firing on Ukrainian positions from an effective safe zone,'” the Institute's latest report said. The head of the U.N. Nuclear watchdog agency earlier this week voiced alarm over the situation at the Zaporizhzhia plant.

In northern Ukraine, the country's second-largest city, Kharkiv, was being shelled from Russia, the presidential office said. Several industrial facilities were hit in the city, which also has been a frequent target. In the nearby city of Chuhuiv, a rocket hit a five-story residential building.

In the eastern Donetsk region, where fighting has been focused in recent weeks, residential buildings were being shelled in all large cities and a school was destroyed in the village of Ocheretyne. The region is struggling without gas supplies and, in part, without power and water supplies; its residents are being evacuated.