- A MiG 21 fighter jet crashes in Kangra district of Himachal Pradesh: Police.
- Govt is ready for discussion on any issue raised by different political parties: PM Modi
- PM Narendra Modi calls for extensive discussion on important issues of national interest
- Two bodies pulled out of rubble of six-storey under-construction building that collapsed
HEALTH & FITNESS
More potent, safer Zika vaccine developed
Scientists have developed the world's first plant-based Zika vaccine that may be more effective, safer and cheaper than other vaccines against the mosquito-borne virus.
Currently, there are no licensed vaccines or therapeutics available to combat Zika, researchers said.
The vaccine developed by researchers from Arizona State University (ASU) in the US works against a part of a Zika viral protein, called DIII, that plays a key role for the virus to infect people.
"All flaviviruses have the envelope protein on the outside part of the virus. It has three domains," said Qiang Chen, a scientist at ASU.
"The domain III has a unique stretch of DNA for the Zika virus, and we exploited this to generate a robust and protective immune response that is unique for Zika," said Chen, who led the research published in the journal Scientific Reports.
The researchers first grew the envelope protein in bacteria, then prepared the DIII protein domain in tobacco plants.
The team then performed immunisation experiments in mice, which induced antibody and cellular immune responses that have been shown to confer 100 per cent protection against multiple Zika virus strains in mice.
The team's protein-based vaccine uses the smallest and most unique part of the Zika virus that can still elicit a potent and robust immune response.
"In our approach, we make what we call a pseudovirus. It is a fake virus. The pseudovirus displays only the DIII part of the envelope protein on the surface," said Chen.
"We did a test to make sure that the vaccine produces a potent protective immune response, but also, that it does not produce antibodies that may be cross reactive for dengue, West Nile, yellow fever or others," he said.
The worldwide Zika threat first emerged in 2015, infecting millions as it swept across the Americas.
It struck great fear in pregnant women, as babies born with severe brain birth defects quickly overburdened hospitals and public health care systems.
- Scent of coffee may help you crack GMAT: Study 18 Jul 2018 | PTI
- Unhealthy fat, cholesterol linked with lower fertility 17 Jul 2018 | IANS
- Brain area linked to binge eating identified 17 Jul 2018 | IANS
- Can a magnetic wire help early detection of cancer 17 Jul 2018 | IANS
- 4 in 10 Indians unaware of cyberbullying: Study 17 Jul 2018 | IANS
- Childhood infections may affect academic performance 17 Jul 2018 | PTI
- Younger pregnant women at high risk of prenatal depression: Study 17 Jul 2018 | IANS
- Nano bubbles filled with drug may kill cancer cells 16 Jul 2018 | IANS
- Empanelled hospitals to have Ayushman Mitra to assist patients seeking treatment under the scheme 16 Jul 2018 | PTI
- Ticks are more likely to attack blood group A: Study 16 Jul 2018 | IANS
Sunday EditionView All
15 Jul 2018 | PTI | New Delhi
Amid row over alleged use of derogatory language in a web series while referring to former Prime Minister Rajiv Gandhi, Congress chief Rahul Gandhi on Saturday said the BJP and the RSS believe that freedom of expression must be policed, while he regards it as a fundamental democratic right. “My father lived and died in the service of India...
STATE EDITIONSView All
18 Jul 2018 | Staff Reporter | RAIPUR
A two-month-old infant died due to suffocation after the door of the ‘108 Ambulance Service’ that was carrying him to a hospital malfunctioned and failed to open on time at Dr Bhimrao Ambedkar Hospital here on Tuesday. The Ambulance operators tried to open the door for a couple of hours but failed to open it on time...